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  Laboratory of psychophysiology of emotions |
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Laboratory of psychophysiology of emotions |
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acad. Ivan Pavlov
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Head of the laboratory
Original models of depressive disorders in rats resulting from a psychogenic trauma due to death of the partner from a predator or from zoo-social conflicts are developed in the Laboratory of psychophysiology of emotions.
Clinical investigations of patients with aphasia have shown that drug-induced activation of vasopressin receptors in the brain induces steady recovery of speech (involving the intact hemisphere in the compensatory process), improves verbal memory and attention A new method of treatment of aphasia based on the results of our investigations has been developed and introduced into practice.
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The model of a posttraumatic stress disorder
(PTSD) has been substantiated allowing investigations of
psychophysiological mechanisms of this disease which is increasingly
spread in the modern world. The development of such pathological
conditions revealed reduced noradrenaline and serotonin, disbalance of
vasopressin and galanin in the CNS as well as altered lipid metabolism - a
dramatic and long-standing reduction of alpha-cholesterol in blood.
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extent pf pathology was found to be associated with the social rank of the
animals. Investigations of stress sequels experienced by mothers during
gestation have revealed locomotor disorders in the progeny, impaired
behavior and altered immunoreactivity. These alterations were associated
with the gender, to be changed with age and to depend on the type of
functional asymmetry of the mothers. The disclosure of the mechanisms of
vulnerability and resistance to psycho-damaging factors opens the
possibilities to increase stress-resistance, correction of pathological
states and prophylactics of disturbed behavior in progeny.